The primary aim of this book is to fill the gap in the emerging sub discipline of Healthcare Entrepreneurship. The proposed book is conceptually innovative as there are currently no substantive books that expose students to the theory, process and practice of entrepreneurship by individuals and organizations within the health care context. Given the emerging nature, the growing importance of the sub discipline, and the subtleties and nuances that are unique to this sector, this book can serve as the primary resource for academic programs in healthcare entrepreneurship as well as organizations that wish to embrace this approach in an effort to transform their organizations. This book will provide the rationale and business case for an entrepreneurial approach to the transformation of the health sector as well the potentially high rewards that may accrue from such an approach. It will present a framework for students and practitioners to understand and learn the entrepreneurial process within different business contexts - a new venture, existing organizations, for profit or not for profit organizations, as well as within public or private health sectors. Accordingly, the book will be divided into four broad segments: rationale, concepts, contexts, and case studies. The book offers a presentation of new and adapted models that contextualize entrepreneurship to healthcare, a strong focus on opportunity recognition and opportunity assessment in the healthcare sector and end of chapter short cases.